The U.S. military said it carried out four airstrikes Wednesday targeting anti-ship cruise missiles located in Houthi-controlled areas of Yemen.
U.S. Central Command said the strikes hit seven mobile cruise missiles and a missile launcher that were ready to launch toward the Red Sea.
U.S. forces also shot down a one-way attack drone, CENTCOM said.
The strikes were carried out in response to what CENTCOM called "an imminent threat to merchant vessels and to the U.S. Navy ships in the region."
Houthi militants have conducted dozens of attacks since November, disrupting the key Red Sea shipping route. Many shipping companies have opted to avoid the area, taking the longer and more expensive route of sending ships around Africa.
Wednesday’s strikes came a day after the Pentagon confirmed the Iran-backed Houthis shot down a MQ-9 Reaper drone off the coast of Yemen.
The United States on Wednesday condemned the Houthi attacks in the Red Sea, saying they are delaying and increasing the costs for food and medicine deliveries to parts of the world in need of humanitarian aid.
"Contrary to what the Houthis may attempt to claim, their attacks do nothing to help the Palestinians," U.S. State Department spokesperson Matthew Miller said in a statement. "Their actions are not bringing a single morsel of assistance or food to the Palestinian people."