Three sons of Hamas leader Ismail Haniyeh were killed in an Israeli airstrike in the Gaza Strip on Wednesday, the Palestinian Islamist group and Haniyeh's family said,
Reuters reports.
The Israeli military said it was checking the report.
Haniyeh, based abroad in Qatar, has been the tough-talking face of Hamas' international diplomacy as war with Israel has raged on in Gaza, where his family home was destroyed in an Israeli airstrike back in November.
The three sons - Hazem, Amir and Mohammad - were killed after the car they were driving in was bombed in Gaza's Al-Shati camp, Hamas said. Three of Haniyeh's grandchildren were also killed in the attack and a third was wounded, Hamas media said.
"The blood of my sons is not dearer than the blood of our people," Haniyeh, 61, who has 13 sons and daughters according to Hamas sources, told pan-Arab Al Jazeera TV.
The three sons and three grandchildren were making family visits during the first day of the Muslim Eid al-Fitr holiday in Shati, their home refugee camp in Gaza City, according to relatives.
Hamas said on Tuesday it was studying an Israeli ceasefire proposal in the more than six-month-old Gaza war but that it was "intransigent" and met none of the Palestinian demands.
"Our demands are clear and specific and we will not make concessions on them. The enemy will be delusional if it thinks that targeting my sons, at the climax of the negotiations and before the movement sends its response, will push Hamas to change its position," Haniyeh said.
In the seventh month of a war in which Israel's air and ground offensive has devastated Gaza, Hamas wants an end to Israeli military operations and a withdrawal from the enclave, and permission for displaced Palestinians to return home.
Haniyeh's eldest son confirmed in a Facebook post that his three brothers were killed. "Thanks to God who honoured us by the martyrdom of my brothers, Hazem, Amir and Mohammad and their children," wrote Abdel-Salam Haniyeh.
