An Israeli air strike is reported to have killed dozens of people at Jabalia refugee camp in northern Gaza,
BBC reports.
Gaza's Hamas-run health ministry said 50 people were killed and 150 wounded. But a nearby hospital said it received 400 casualties, including 120 dead.
Pictures showed several large craters, surrounded by shattered buildings.
The Israeli military said the strike killed a senior Hamas commander and "underground terror infrastructure" beneath buildings collapsed afterwards.
It added that a "large number of terrorists" from Hamas's Central Jabalia Battalion who had been with the commander at the time were also killed.
Israeli tanks and troops, meanwhile, continued to advance towards some of northern Gaza's most populated areas, including Jabalia.
Israel has said it is the "second phase" of its war to eliminate Hamas, which began after an unprecedented cross-border attack by gunmen from Gaza on 7 October in which 1,400 people were killed and another 240 taken hostage.
Gaza's health ministry says more than 8,500 people have been killed in the territory since then, while supplies of food, water, fuel and medicine for its 2.2 million residents are dangerously low because of a siege imposed by Israel.
Tuesday's air strike in Jabalia caused a huge explosion that destroyed several residential buildings in the centre of the refugee camp, where before the war 116,000 people were living in an area of just 1.4 sq km (0.5 sq miles).