Scattered trees and debris landed on roads and homes in Little Rock, Arkansas, on Friday (March 31) after a fierce tornado blasted through the city, Reuters reports.
Footage from ABC affiliate KATV shows damaged vehicles, houses and streets in the state's capital.
The University of Arkansas for Medical Sciences declared a mass-casualty event after a "catastrophic" tornado hit Little Rock on Friday, a CBS affiliate reported, adding hundreds of people were injured.
The National Weather Service also reported that tornado activity had destroyed several homes and downed trees in and around Little Rock.
The twister struck the capital city of Arkansas as an immense blast of extreme spring weather swept much of the United States, menacing the nation's midsection from Texas to the Great Lakes with dangerous thunderstorms and tornadoes.
The weather service issued tornado watches for a region stretching from east Texas through the mid-South and Midwest as far north as Wisconsin, urging some 15 million people living in that area to prepare for violent twisters on Friday afternoon and evening.