The most senior US general estimates that around 100,000 Russian and 100,000 Ukrainian soldiers have been killed or injured in the hostilities in Ukraine, BBC reports. Gen Mark Milley, chairman of the US Joint Chiefs of Staff, also suggested that around 40,000 civilians had died after being caught up in the conflict.
The estimates are the highest offered yet by a Western official.
He also said that signs Kyiv was willing to re-enter talks with Moscow offered "a window" for negotiations.
Speaking in New York, Gen Milley added that for any talks to be successful, both Russia and Ukraine would have to reach a "mutual recognition" that a wartime victory "is maybe not achievable through military means, and therefore you need to turn to other means".
The top general - who serves as President Joe Biden's most senior military adviser - said the scale of the casualties could convince both Moscow and Kyiv of the need to negotiate over the coming winter months, when fighting may slow due to freezing conditions.
